Recombinant Human MRM1, His-tagged

• Cat.No.: MRM1-7594H
• Product Overview: Recombinant human MRM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Antigen Description: Mitochondrial rRNA methyltransferase 1 homolog, also known as MRM1, probably methylates the ribose of guanosine G-2270 in the peptidyl transferase center of the mitochondrial large ribosomal RNA (21S).
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT, 0.1mM PMSF
• Molecular Mass: 38.8 kDa (356aa) confirmed by MALDI-TOF
• Protein length: 21-353aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSSHAARHG ERPGGEELSR LLLDDLVPTS RLELLFGMTP CLLALQAARR SVARLLLQAG KAGLQGKRAE LLRMAEARDI PVLRPRRQKL DTMCRYQVHQ GVCMEVSPLR PRPWREAGEA SPGDDPQQLW LVLDGIQDPR NFGAVLRSAH FLGVDKVITS RRNSCPLTPV VSKSSAGAME VMDVFSTDDL TGFLQTKAQQ GWLVAGTVGC PSTEDPQSSE IPIMSCLEFL WERPTLLVLG NEGSGLSQEV QASCQLLLTI LPRRQLPPGL ESLNVSVAAG ILLHSICSQR KGFPTEGERR QLLQDPQEPS ARSEGLSMAQ HPGLSSGPEK ERQNEG
• Purity: >90% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml

Gene Information

• Gene Name: MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: MRM1
• Synonyms: MRM1; mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae); rRNA methyltransferase 1, mitochondrial; FLJ22578; mitochondrial large ribosomal RNA ribose methylase
• Gene ID: 79922
• mRNA Refseq: NM_024864
• Protein Refseq: NP_079140
• UniProt ID: Q6IN84
• Chromosome Location: 17q12
• Function: RNA binding; RNA methyltransferase activity; transferase activity