Recombinant Human ADP-Ribosylation Factor-Like 1, His-tagged

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Recombinant Human ADP-Ribosylation Factor-Like 1, His-tagged

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Cat. No. : ARL1-4200H
Product Overview : ARL1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 201 amino acids (1-181 a.a.) and having a molecular mass of 22.5 kDa. The ARL1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Description : ARL1 is part of the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally associated to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, control intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. ARL1 is a weak stimulator of PLD and CT in a phospholipid dependent manner. ARL1 is a GTP-binding protein that has low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. ARL1 is involved in the Golgi apparatus.
Source : Human
Host : Escherichia Coli.
Form : 0.25mg/ml solution containing 20mM Tris pH-8, 1mM DTT & 10% glycerol.
Purity : Greater than 95.0% as determined by SDS-PAGE.
Physical Appearance : Sterile filtered colorless solution.
Amino acid sequence : MGSSHHHHHH SSGLVPRGSH MGGFFSSIFS SLFGTREMRI LILGLDGAGK TTILYRLQVG EVVTTIPTIG FNVETVTYKN LKFQVWDLGG QTSIRPYWRC YYSNTDAVIY VVDSCDRDRI GISKSELVAM LEEEELRKAI LVVFANKQDM EQAMTSSEMA NSLGLPALKD RKWQIFKTSA TKGTGLDEAM EWLVETLKSR Q.
Storage : ARL1 Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
PDBrendering based on 1r4a. :

Gene Name : ARL1 ADP-ribosylation factor-like 1 [ Homo sapiens ]
Official Symbol : ARL1
Synonyms : ARL1; ADP-ribosylation factor-like 1; ARFL1; ADP-ribosylation factor-like protein 1
Gene ID : 400
mRNA Refseq : NM_001177
Protein Refseq : NP_001168
MIM : 603425
UniProt ID : P40616
Chromosome Location : 12q23.2
Function : GTP binding; GTPase activity; enzyme activator activity; metal ion binding; nucleotide binding; protein binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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