Recombinant Human Lymphatic Vessel Endothelial Hyaluronan Receptor 1

• Cat.No.: LYVE1-906H
• Product Overview: LYVE1 Human Recombinant produced in insect cells is a single, glycosylated polypeptide chain containing 229 amino acids and having a molecular mass of 24.8 kDa. As a result of glycosylation, the LYVE1 migrates on SDS-PAGE at approximately 50 kDa.

Specification

• Cat. No.: LYVE1-906H
• Description: LYVE1 is a selective marker of the lymphatic endothelium & a surface endocytic receptor for both soluble and immobilized hyaluronan, LYVE1 is an extracellular glycosaminoglycan that plays a role in cell adhesion and migration. LYVE1 functions in lympathic hyaluronan transport and is involved in tumor metastasis.
• Source: Human
• Host: High Five insect cells
• Form: The LYVE1 protein solution contains 20 mM Tris buffer pH-7.5 and 10 % Glycerol.
• Purity: Greater than 90.0% as determined by (a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
• Physical Appearance: Sterile Filtered colorless solution.
• Amino acid sequence: DPLRAEELS IQVSCRIMGI TLVSKKANQQ LNFTEAKEAC RLLGLSLAGK DQVETALKAS FETCSYGWVG DGFVVISRIS PNPKCGKNGV GVLIRKVPVS RQFAAYCYNS SDTWTNSCIP EIITTKDPIF NTQTATQTTE FIVSDSTYSV ASPYSTIPAP TTTPPAPAST SIPRRKKLIC VTEVFMETST MSTETEPFVE NKAAFKNEAA GFGGSGRLVP RGSHHHHHH
• Storage: LYVE1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1 % HSA or BSA). Please prevent freeze-thaw cycles.

Gene Information

• Gene Name: LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 [ Homo sapiens ]
• Official Symbol: LYVE1
• Synonyms: LYVE1; lymphatic vessel endothelial hyaluronan receptor 1; HAR; XLKD1; LYVE-1; CRSBP-1; lymphatic vessel endothelial hyaluronic acid receptor 1; OTTHUMP00000230796; OTTHUMP00000230798;hyaluronic acid receptor; extracellular link domain containing 1; extracellular link domain-containing 1; extracellular link domain-containing protein 1; cell surface retention sequence binding protein-1; cell surface retention sequence-binding protein 1; UNQ230/PRO263
• Gene ID: 10894
• mRNA Refseq: NM_006691
• Protein Refseq: NP_006682
• MIM: 605702
• UniProt ID: Q9Y5Y7
• Chromosome Location: 11p15
• Function: binding; hyaluronic acid binding; receptor activity; transmembrane receptor activity