Recombinant Human Mitogen-Activated Protein Kinase 1
Cat.No. : | MAPK1-896H |
Product Overview : | MAPK1 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 380 amino acids (1-360 a.a.) and having a molecular mass of 43.5 kDa. The MAPK1 is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
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Cat. No. : | MAPK1-896H |
Description : | Mitogen-activated protein kinase 1 (MAPK1) is also known as "extracellular signal-regulated kinase 2" (ERK2). Two similar (85% sequence identity) protein kinases were originally called ERK1 and ERK2. |
Source : | Human |
Host : | Escherichia Coli |
Form : | The MAPK1 solution contains 20 mM Tris-HCl buffer (pH 8.0), 1mM DTT and 10% glycerol. |
Purity : | Greater than 95.0% as determined by SDS-PAGE. |
Physical Appearance : | Sterile Filtered colorless solution. |
Amino acid sequence : | MGSSHHHHHH SSGLVPRGSH MAAAAAAGAG PEMVRGQVFD VGPRYTNLSY IGEGAYGMVC SAYDNVNKVR VAIKKISPFE HQTYCQRTLR EIKILLRFRH ENIIGINDII RAPTIEQMKD VYIVQDLMET DLYKLLKTQH LSNDHICYFL YQILRGLKYI HSANVLHRDL KPSNLLLNTT CDLKICDFGL ARVADPDHDH TGFLTEYVAT RWYRAPEIML NSKGYTKSID IWSVGCILAE MLSNRPIFPG KHYLDQLNHI LGILGSPSQE MGSSHHHHHH SSGLVPRGSH MAAAAAAGAG PEMVRGQVFD VGPRYTNLSY IGEGAYGMVC SAYDNVNKVR VAIKKISPFE HQTYCQRTLR EIKILLRFRH ENIIGINDII RAPTIEQMKD VYIVQDLMET DLYKLLKTQH LSNDHICYFL YQILRGLKYI HSANVLHRDL KPSNLLLNTT CDLKICDFGL ARVADPDHDH TGFLTEYVAT RWYRAPEIML NSKGYTKSID IWSVGCILAE MLSNRPIFPG KHYLDQLNHI LGILGSPSQE DLNCIINLKA RNYLLSLPHK NKVPWNRLFP NADSKALDLL DKMLTFNPHK RIEVEQALAH PYLEQYYDPS DEPIAEAPFK FDMELDDLPK EKLKELIFEE TARFQPGYRS. |
Storage : | MAPK1 although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Gene Name : | MAPK1 mitogen-activated protein kinase 1 [ Homo sapiens ] |
Official Symbol : | MAPK1 |
Synonyms : | MAPK1; mitogen-activated protein kinase 1; ERK; p38; p40; p41; ERK2; ERT1; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK; MAP kinase 2; Mitogen-activated protein kinase 2; Extracellular signal-regulated kinase 2; OTTHUMP00000174492; protein tyrosine kinase ERK2 |
Gene ID : | 5594 |
mRNA Refseq : | NM_002745 |
Protein Refseq : | NP_002736 |
MIM : | 176948 |
UniProt ID : | P28482 |
Chromosome Location : | 22q11.2; 22q11.21 |
Function : | ATP binding; MAP kinase 2 activity; mitogen-activated protein kinase kinase kinase binding; nucleotide binding; phosphotyrosine binding; protein binding; protein serine/threonine kinase activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
MAPK1-1081H | Recombinant Human MAPK1 Protein (M1-S360), Flag/His tagged | +Inquiry |
MAPK1-1080H | Recombinant Human MAPK1 Protein (M1-S360), Tag Free | +Inquiry |
MAPK1-1361H | Recombinant Human MAPK1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAPK1-2008H | Recombinant Human MAPK1 Protein, GST-tagged | +Inquiry |
MAPK1-385H | Recombinant Human MAPK1 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
MAPK1-692HCL | Recombinant Human MAPK1 cell lysate | +Inquiry |
MAPK1-001MCL | Recombinant Mouse MAPK1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMAPK1 expression and activity levels can be used as biomarkers to assess cancer risk and prognosis.
MAPK1 inhibitors are being explored for potential use in non-cancer conditions, such as heart disease and neurodegenerative disorders.
MAPK1 is also implicated in various other diseases, including cardiovascular diseases and neurological disorders.
Yes, there are targeted therapies that aim to inhibit MAPK1, especially in cases where MAPK1 is overactive in cancer cells.
Yes, by assessing the MAPK1 status in a patient's cells, healthcare providers can develop personalized treatment plans.
Customer Reviews (3)
Write a reviewWhether it be troubleshooting issues, offering experimental guidance, or addressing any concerns, the manufacturer's technical support ensures that researchers have a reliable and knowledgeable resource to rely on.
In addition to its scientific merits, the manufacturer of MAPK1 protein stands out for its outstanding technical support.
The company provides a dedicated team of experts who are readily available to assist researchers throughout their experimental journey.
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