"MYL1" Related Products


Recombinant Human Myosin, Light Chain 1, Alkali; Skeletal, Fast

Cat. No.: MYL1-4457H
Product Overview: Recombinant Human Ventricular Myosin Light Chain-1 (MYL1) protein has a molecular mass of 25 kDa and is fused to 7 amino acids at N-terminus. The MYL1 protein was affinity purified using anti MYL1 monoclonal antibody 39-15 column.
Description: Myosin is a hexameric ATPase cellular motor protein, which is composed of 2 heavy chains, 2 non-phosphorylatable alkali light chains, and 2 phosphorylatable regulatory light chains. MYL1 gene encodes a myosin alkali light chain expressed in fast skeletal muscle. Two transcript variants have been identified for the MYL1 gene. In humans MYL1 is localized to chromosome 2q32.1-qter. The Myl1 locus encodes two alkali myosin light chains- Mlc1f and Mlc3f, from two promoters that are differentially regulated throughout development. The Mlc1f promoter is active in embryonic, fetal and adult fast skeletal muscle while the Mlc3f promoter is upregulated during fetal development and stays on in adult fast skeletal muscle.
Source: Human
Host: Escherichia Coli.
Form: Human MYL1 in 10mM Tris -HCI, 1mM EDTA PH 7.5.
Purity: Greater than 90.0% as determined by SDS-PAGE.
Physical Appearance: Sterile Filtered clear solution.
Storage: Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.
Pathways: G13 Signaling Pathway; Muscle contraction; Regulation of Actin Cytoskeleton; Striated Muscle Contraction
Gene Name: MYL1 myosin, light chain 1, alkali; skeletal, fast [ Homo sapiens ]
Official Symbol: MYL1
Synonyms: MYL1; myosin, light chain 1, alkali; skeletal, fast; MLC1F; MLC3F; myosin light chain 1/3, skeletal muscle isoform; MLC1/MLC3; MLC1F/MLC3F; A1 catalytic; 2 catalytic; OTTHUMP00000163941; OTTHUMP00000163942; myosin light chain A1/A2; myosin light chain alkali 1/2; myosin, light polypeptide 1, alkali; skeletal, fast
Gene ID: 4632
mRNA Refseq: NM_079420
Protein Refseq: NP_524144
MIM: 160780
UniProt ID: P05976
Chromosome Location: 2q33-q34
Function: calcium ion binding; structural constituent of muscle

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