"NACA" Related Products

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Recombinant Human Nascent Polypeptide-Associated Complex Alpha Subunit, His-tagged

Cat. No.: NACA-1286H
Product Overview: Recombinant human NACA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: NACA is member of the nascent polypeptide associated complex (NAC) alpha subunit family that participate in preventing inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Most NACA proteins localize to both nucleus as well as cytoplasm, and contain NAC-A/B (NAC-alpha/beta) and UBA (ubiquitin-associated) domains. The UBA domain is associated with proteins involved in the ubiquitin-proteasome pathway for protein degradation.
Form: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.
Molecular Weight: 25.5 kDa (235aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Purity: > 95 % by SDS - PAGE
Concentration: 1 mg/ml (determined by BCA)
Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MPGEATETVP ATEQELPQPQ AETGSGTESD SDESVPELEE QDSTQATTQQ AQLAAAAEID EEPVSKAKQS RSEKKARKAM SKLGLRQVTG VTRVTIRKSK NILFVITKPD VYKSPASDTY IVFGEAKIED LSQQAQLAAA EKFKVQGEAV SNIQENTQTP TVQEESEEEE VDETGVEVKD IELVMSQANV SRAKAVRALK NNSNDIVNAI MELTM
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: NACA nascent polypeptide-associated complex alpha subunit [ Homo sapiens ]
Official Symbol: NACA
Synonyms: NACA; nascent polypeptide-associated complex alpha subunit; HSD48; NACA1; MGC117224; nascent polypeptide-associated complex subunit alpha; NAC-alpha; alpha-NAC; Alpha-NAC; Allergen Hom s 2; nascent-polypeptide-associated complex alpha polypeptide; Nascent polypeptide-associated complex subunit alpha
Gene ID: 4666
mRNA Refseq: NM_001113201
Protein Refseq: NP_001106672
MIM: 601234
UniProt ID: Q13765
Chromosome Location: 12q23-q24.1
Function: DNA binding

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