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Recombinant Human SFTPD protein(Met1-Phe375), His-tagged

Cat.No. : SFTPD-3868H
Product Overview : Recombinant Human SFTPD (NP_003010.4)(Met 1-Phe 375) was expressed in HEK293, fused with a polyhistidine tag at the C-terminus.
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Source : HEK293
Species : Human
Tag : C-His
Protein length : Met1-Phe375
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The pro form of human SFTPD consists of 366 amino acids and predictes a molecular mass of 37 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of SFTPD is 47 kDa due to glycosylation.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : > 90 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Publication :
Surfactant Proteins-A and -D Attenuate LPS-Induced Apoptosis in Primary Intestinal Epithelial Cells (IECs) (2018)
Gene Name : SFTPD surfactant protein D [ Homo sapiens ]
Official Symbol : SFTPD
Synonyms : SFTPD; surfactant protein D; SFTP4, surfactant, pulmonary associated protein D; pulmonary surfactant-associated protein D; COLEC7; SP D; collectin 7; collectin-7; lung surfactant protein D; pulmonary surfactant apoprotein; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4; SP-D; PSP-D; SFTP4;
Gene ID : 6441
mRNA Refseq : NM_003019
Protein Refseq : NP_003010
MIM : 178635
UniProt ID : P35247

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How is SFTPD involved in the regulation of inflammation? 02/14/2022

SFTPD regulates immune cell activity, helping to control inflammation in the lungs.

Are there known genetic variations in SFTPD associated with specific diseases? 09/04/2021

Certain genetic variations in SFTPD have been linked to increased susceptibility to respiratory diseases.

What is the primary function of SFTPD in the immune system? 08/15/2020

SFTPD enhances the clearance of pathogens and modulates immune responses.

What role does SFTPD play in respiratory infections? 06/15/2020

It binds to pathogens, aiding in their clearance and protecting against respiratory infections.

What therapeutic strategies are being explored that involve SFTPD? 03/30/2020

Therapies are being explored to modulate SFTPD levels in diseases like COPD and pulmonary fibrosis.

How does SFTPD contribute to pulmonary homeostasis? 01/01/2019

It maintains lung function by participating in surfactant homeostasis and immune regulation.

In which tissues is SFTPD predominantly expressed? 10/13/2018

SFTPD is primarily expressed in the lungs, especially in alveolar and bronchiolar epithelial cells.

Customer Reviews (3)

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Reviews
11/17/2022

    Quality product, fast delivery.

    04/21/2021

      Fast, efficient, and reliable.

      02/06/2018

        Excellent performance in assay.

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