Recombinant Human Tribbles Homolog 2 (Drosophila), GST-tagged

• Cat.No.: TRIB2-3852H
• Product Overview: A DNA sequence encoding the human TRIB2 ( NP_006204.1 ) (Met 1-Asn 343) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Specification

• Cat. No.: TRIB2-3852H
• Description: TRIB2 is a member of the protein kinase superfamily and Tribbles subfamily (Trib1, Trib2, Trib3). The identification of tribbles as regulators of signal processing systems and physiological processes, including development, together with their potential involvement in diabetes and cancer, has generated considerable interest in these proteins.
• Source: Human
• Host: Baculovirus
• Form: Lyophilized from sterile 50mM Tris, 100mM NaCl, 0.5mM PMSF, 0.5mM GSH, pH 8.0. Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
• Purity: > 82 % as determined by SDS-PAGE
• Endotoxin: μ1.0 EU per μg protein as determined by the LAL method
• Stability: Samples are stable for up to twelve months from date of receipt at -70°C.
• Predicted N terminal: Met
• Molecular Mass: The recombinant human TRIB2/GST chimera consists of 580 amino acids and predicts a molecular mass of 66.6 kDa. It migrates as an approximately 60 kDa band in SDS-PAGE under reducing conditions.
• Storage: Store it under sterile conditions at -70°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: TRIB2 tribbles homolog 2 (Drosophila) [ Homo sapiens ]
• Official Symbol: TRIB2
• Synonyms: TRIB2; tribbles homolog 2 (Drosophila); C5FW; TRB2; GS3955; FLJ57420; tribbles homolog 2; OTTHUMP00000115687
• Gene ID: 28951
• mRNA Refseq: NM_021643
• Protein Refseq: NP_067675
• MIM: 609462
• UniProt ID: Q92519
• Chromosome Location: 2p24.3
• Function: ATP binding; NOT nucleotide binding; NOT protein kinase activity; protein kinase inhibitor activity; transcription factor binding; transferase activity; ubiquitin protein liqase binding; ubiquitin-protein liqase requator activity