| Cat. No. : |
KIAA1967-3705H |
| Description : |
KIAA1967, also known as Deleted in Breast Cancer 1, is a protein which in humans is encoded by the KIAA1967 gene. Recent studies show that KIAA1967 is an inhibitor of the sirtuin-type deacetylase, SIRT1, which deacetylateshistones and p53. KIAA1967 is likely to regulate the activity of SIRT1 or related deacetylases by sensing the soluble products or substrates of the NAD-dependent deacetylation reaction. |
| Source : |
E. coli |
| Species : |
Human |
| Form : |
Filtered (0,4μm) and lyophilized in 0.5mg/mL in 0.05M MES bufferpH6.5 |
| Researchtopic : |
Energy metabolism and body weight regulation |
| Purity : |
>95% |
| Reconstitution : |
Add deionized water to prepare a working stock solution of approximately 0.5mg/mL and let the lyophilized pellet dissolve completely. This product typically requires 20min at 37°C for complete reconstitution. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10μg/ml. In higher concentrations the solubility of this antigen is limited. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. |
| Applications : |
Western blotting |
| QualityControl Test : |
BCA to determine quantity of the protein; SDS PAGE to determine purity of the protein |
| Sequences of aminoacids : |
MKHHHHHHHM IKKNLKKLGI EETYLNIIKA IYDRPTASIQ KTENLSTKTG TSQEYHLSPL WFYIVLEILA STIRQEKNLK DIHTEKEEVK LSLFADAMIL YLKKPNDSTR KLLELIKKIH SSCRIKINIH FAFCSQ |
| Storage : |
Store lyophilized protein at -20°C. Lyophilized protein remains stable until the expiry date when stored at -20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at -80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after one week at4°C. |
