Recombinant Human CRCP, His-tagged

• Cat.No.: CRCP-3633H
• Product Overview: Recombinant human CRCP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography (1-148aa).

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: CRCP, also known as CGRP-RCP, is an ubiquitous coupling protein for the calcitonin gene-related peptide and adrenomedullin receptors. It modulates ligand responsiveness in a variety of tissues. It has been DNA-directed RNA polymerase activity, catalytic activity and calcitonin receptor activity.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
• Molecular Weight: 19.0 kDa(168aa), confirmed by MALDI-TOF
• Purity: > 95% by SDS - PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MEVKDANSAL LSNYEVFQLL TDLKEQRKES GKNKHSSGQQ NLNTITYETL KYISKTPCRH QSPEIVREFL TALKSHKLTK AEKLQLLNHR PVTAVEIQLM VEESEERLTE EQIEALLHTV TSILPAEPEA EQKKNTNSNV AMDEEDPA
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: CRCP CGRP receptor component [ Homo sapiens ]
• Official Symbol: CRCP
• Synonyms: CRCP; RCP; RCP9; CGRPRCP; CGRP-RCP; MGC111194; hsC17; HsC17; CGRP receptor component; DNA-directed RNA polymerase III subunit RPC9; OTTHUMP00000159905; OTTHUMP00000210319; OTTHUMP00000210320; OTTHUMP00000210321; RNA polymerase III subunit C9; CGRP-receptor component protein; calcitonin gene-related peptide-receptor component protein
• Gene ID: 27297
• mRNA Refseq: NM_001040647
• Protein Refseq: NP_001035737
• MIM: 606121
• UniProt ID: O75575
• Chromosome Location: 7q11.21
• Function: DNA-directed RNA polymerase activity; calcitonin gene-related polypeptide receptor activity; calcitonin receptor activity; catalytic activity; nucleotide binding