"CRYM" Related Products

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Recombinant Human Crystallin, Mu, His-tagged

Cat. No.: CRYM-2493H
Product Overview: Recombinant human CRYM, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques.MW = 35.9 kDa (334aa).
Description: Crystallin mu, also known as CRYM, is a member of the crystallin protein family. Crystallins are separated into two classes, taxon-specific and ubiquitous. This gene encodes a taxon-specific crystallin protein. The human CRYM gene maps to chromosome 16p13.11, and encodes a protein that is expressed in neural tissue, muscle, and kidney. Unlike other crystallins, CRYM does not perform a structural role in lens tissue, but rather it binds NADPH and thyroid hormone, which indicates that it may have other regulatory or developmental functions.
Source: E.coli.
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol.
Purity: > 95% by SDS – PAGE.
Concentration: 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSRVPAFLSA AEVEEHLRSS SLLIPPLETA LANFSSGPEG GVMQPVRTVV PVTKHRGYLG VMPAYSAAED ALTTKLVTFY EDRGITSVVP SHQATVLLFE PSNGTLLAVM DGNVITAKRT AAVSAIATKF LKPPSSEVLC ILGAGVQAYS HYEIFTEQFS FKEVRIWNRT KENAEKFADT VQGEVRVCSS VQEAVAGADV IITVTLATEP ILFGEWVKPG AHINAVGASR PDWRELDDEL MKEAVLYVDS QEAALKESGD VLLSGAEIFA ELGEVIKGVK PAHCEKTTVF KSLGMAVEDT VAAKLIYDSW SSGK.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name: CRYM crystallin, mu [ Homo sapiens ]
Synonyms: crystallin, mu; THBP; DFNA40; CRYM; mu-crystallin homolog; OTTHUMP00000115878; NADP-regulated thyroid-hormone binding protein; NADP-regulated thyroid-hormone-binding protein
Gene ID: 1428
mRNA Refseq: NM_001014444
Protein Refseq: NP_001014444
MIM: 123740
UniProt ID: Q14894
Chromosome Location: 16p13.11-p12.3
Function: NADP or NADPH binding; catalytic activity; protein homodimerization activity; thyroid hormone binding; transcription corepressor activity

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