Mouse anti-HBe Monoclonal Antibody(lable)

• Cat.No.: CAB046

Specification

• Species: Human
• Source: Ascites
• Tag: Non
• Antigen information: Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA(pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA.
• Specificity: HBe-Ag
• Clone: LT04
• Host Animal: Mouse. Hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice.
• Immunogen: hepatitis virus granule
• Format: Purified, Liquid
• Purification: >90% pure (SDS-PAGE). Protein A chromatography
• Concentration: 6.0mg/ml (OD280nm, E0.1% = 1.4)
• Affinity Constant: 1X1011L/Mol
• Buffer: PBS, pH 7.4
• Preservative: 0.1% NaN3
• Applications: Detection for HBe antigen. Suitable for use in ELISA, Western-Blotting and tissue immunity, Suggested pair for ELISA immunoassay:Capture DetectionCAB045 CAB046
• Storage: Short term at 2-8℃,Long term at -20℃