Recombinant Human Cathepsin S
Cat.No. : | CTSS-1651H |
Product Overview : | Recombinant human CTSS was expressed by Human spleen. |
- Specification
- Gene Information
- Related Products
Cat. No. : | CTSS-1651H |
Description : | Like Cathepsins B, H, and L, CTSS belongs to the group of lysosomal cysteine proteinases. CTSS is found primarily in the spleen and in lung macrophages. Its level is elevated in the brain tissue of those with Alzheimer"s disease and Down syndrome. CTSS may function in the processing of amyloid precursor protein to amyloid beta peptides. |
Biological Activity : | 229.9 mU/mg using the method described by Kirche & Weiderlanders in Methods in Enzymology, 244. |
Source : | Human spleen |
Species : | Human |
Form : | Lyophilized from 8.36 ul of 100 mM NaAc+1 mM EDTA, pH 5.5. |
Appearance : | Lyophilized |
Reconstitution : | Reconstitute in water to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. |
Storage : | Store at -70°C, stable for at least 1 year as supplied. Avoid freeze/thaw cycles. |
Pathways : | Antigen processing and presentation; Lysosome; Phagosome; Tuberculosis |
Gene Name : | CTSS cathepsin S [ Homo sapiens ] |
Official Symbol : | CTSS |
Synonyms : | CTSS; cathepsin S; MGC3886; FLJ50259; OTTHUMP00000032942; EC 3.4.22.27 |
Gene ID : | 1520 |
mRNA Refseq : | NM_004079 |
Protein Refseq : | NP_004070 |
MIM : | 116845 |
UniProt ID : | P25774 |
Chromosome Location : | 1q21 |
Function : | cysteine-type endopeptidase activity; peptidase activity |
Products Types
◆ Recombinant Protein | ||
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Ctss-1293R | Recombinant Rat Ctss Protein, His-tagged | +Inquiry |
CTSS-2118H | Recombinant Human CTSS Protein, GST-tagged | +Inquiry |
CTSS-1329R | Recombinant Rat CTSS Protein, His (Fc)-Avi-tagged | +Inquiry |
ctss-2767M | Recombinant Mouse ctss protein, His-tagged | +Inquiry |
◆ Native Protein | ||
CTSS-27405TH | Native Human CTSS | +Inquiry |
◆ Lysates | ||
CTSS-3021HCL | Recombinant Human CTSS cell lysate | +Inquiry |
CTSS-1563MCL | Recombinant Mouse CTSS cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-2353 | Cathepsin S Inhibitor Screening Kit (Fluorometric) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe function of CTSS proteins can be studied through gene knockout or knockdown techniques, such as using techniques such as CRISPR-Cas9 or RNAi. These techniques can create cellular models of missing or reduced CTSS proteins to observe their effects on cell death, among other things.
Expression level of CTSS protein can be detected by immunohistochemistry, western blotting, and real-time quantitative PCR.
CTSS proteins promote cell death by degrading proteins inside cells. During apoptosis, CTSS proteins degrade key proteins within cells, leading to cell death.
The interaction between CTSS proteins and other proteins is regulated by the formation of complexes or the regulation of signal transduction pathways. These interactions can be influenced by a variety of factors, such as ion concentrations, neurotransmitters, and growth factors.
Some studies have shown that the expression level of CTSS protein may be associated with the onset and progression of certain diseases. For example, in some cancers, the expression level of the CTSS protein may change.
It is mainly expressed in lysosomes, which is one of the major proteases in lysosomes.
Customer Reviews (3)
Write a reviewHigh catalytic efficiency, short time, saving time.
The solubility is very good and can be easily dissolved in various buffers.
Anti-pollution ability is very strong, not easy to be polluted.
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