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Recombinant Mouse Nicotinamide Phosphoribosyltransferase

Cat. No.: Nampt-1667M
Product Overview: Recombinant full-length (a.a.1-491) mouse Nampt was expressed in E. coli, 55 kDa.
Description: Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt) also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin is an enzyme that in humans is encoded by the PBEF1 gene.This protein has also been reported to be a cytokine (PBEF) that promotes B cell maturation and inhibits neutrophil apoptosis.
Biological Activity: Mimics insulin effects in differentiating 3T3-L1 cells.
Molecular Weight: 55 kDa
Source: E. coli
Species: Mouse
Form: Lyophilized without additives.
Appearance: Lyophilized protein
Endotoxin Level: <0.1 ng/μg
Reconstitution: Reconstitute in PBS to the concentration of 0.1-1 mg/ml.
Purity: >95% by SDS-PAGE and HPLC.
Storage: -20°C.
Pathways: Adipogenesis; Metabolism of vitamins and cofactors; Metabolism of water-soluble vitamins and cofactors; NAD biosynthesis III; Nicotinamide salvaging; Nicotinate and nicotinamide metabolism; Nicotinate metabolism
Gene Name: Nampt nicotinamide phosphoribosyltransferase [ Mus musculus ]
Official Symbol: Nampt
Synonyms: Nampt; nicotinamide phosphoribosyltransferase; Pbef; Pbef1; AI314458; AI480535; Visfatin; NAmPRTase; 1110035O14Rik; pre-B-cell colony-enhancing factor 1 homolog; NP_067499.2; EC 2.4.2.12; DKFZp666B131; pre-B-cell colony enhancing factor 1; MGC117256; Pre-B cell-enhancing factor; OTTHUMP00000179150
Gene ID: 59027
mRNA Refseq: NM_021524
Protein Refseq: NP_067499
UniProt ID: Q99KQ4
Chromosome Location: 12; 12 B1
Function: cytokine activity; drug binding; nicotinamide phosphoribosyltransferase activity; nicotinate phosphoribosyltransferase activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; protein homodimerization activity; transferase activity; transferase activity, transferring glycosyl groups

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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