"GRK7" Related Products


Recombinant Human G Protein-Coupled Receptor Kinase 7, GST-tagged

Cat. No.: GRK7-1021H
Product Overview: Full-length recombinant human GRK7 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: GRK7 is a member of the G protein-coupled receptor kinase subfamily and is a Ser/Thr protein kinase. GRK7 is specifically expressed in the retina and has been shown to phosphorylate cone opsins and initiate their deactivation. GRK7 catalyzes rhodopsin phosphorylation in a light-dependent manner. GRK7 co-localizes with GRK1 in human cone outer segments.
Applications: Kinase Assay; Western Blot
Molecular Weight: 89 kDa
Expression System: Sf9 insect cells using baculovirus
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity: >95%
Concentration: 0.1 ug/ul
Specific Activity: 2.5 nmol/min/mg
Sequences: Full length
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways: Chemokine signaling pathway; Endocytosis; Phototransduction; Visual signal transduction: Cones
Gene Name: GRK7 G protein-coupled receptor kinase 7 [ Homo sapiens ]
Official Symbol: GRK7
Synonyms: GRK7; G protein-coupled receptor kinase 7; GPRK7; G protein-coupled receptor kinase 7; OTTHUMP00000214002; g protein-coupled receptor kinase GRK7
Gene ID: 131890
mRNA Refseq: NM_139209
Protein Refseq: NP_631948
MIM: 606987
UniProt ID: Q8WTQ7
Chromosome Location: 3q24
Function: ATP binding; G-protein coupled receptor kinase activity; nucleotide binding; rhodopsin kinase activity; signal transducer activity

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