"GRK7" Related Products


Recombinant Human G Protein-Coupled Receptor Kinase 7, GST-tagged

Cat. No. : GRK7-1021H
Product Overview : Full-length recombinant human GRK7 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : GRK7 is a member of the G protein-coupled receptor kinase subfamily and is a Ser/Thr protein kinase. GRK7 is specifically expressed in the retina and has been shown to phosphorylate cone opsins and initiate their deactivation. GRK7 catalyzes rhodopsin phosphorylation in a light-dependent manner. GRK7 co-localizes with GRK1 in human cone outer segments.
Applications : Kinase Assay; Western Blot
Molecular Weight : 89 kDa
Expression System : Sf9 insect cells using baculovirus
Species : Human
Form : Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Purity : >95%
Concentration : 0.1 ug/ul
Specific Activity : 2.5 nmol/min/mg
Sequences : Full length
Storage : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways : Chemokine signaling pathway; Endocytosis; Phototransduction; Visual signal transduction: Cones
Gene Name : GRK7 G protein-coupled receptor kinase 7 [ Homo sapiens ]
Official Symbol : GRK7
Synonyms : GRK7; G protein-coupled receptor kinase 7; GPRK7; G protein-coupled receptor kinase 7; OTTHUMP00000214002; g protein-coupled receptor kinase GRK7
Gene ID : 131890
mRNA Refseq : NM_139209
Protein Refseq : NP_631948
MIM : 606987
UniProt ID : Q8WTQ7
Chromosome Location : 3q24
Function : ATP binding; G-protein coupled receptor kinase activity; nucleotide binding; rhodopsin kinase activity; signal transducer activity

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