"MAPK9" Related Products


Recombinant Human Mitogen-Activated Protein Kinase 9, GST-Tagged

Cat. No. : MAPK9-1052H
Product Overview : Recombinant full-length human MAPK9 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : MAPK9 is a member of the JNK family that acts as an integration point for multiple biochemical signals, and is involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. MAPK9 targets specific transcription factors, and mediates immediate-early gene expression in response to various cell stimuli. Both UV radiation and the proinflammatory cytokine TNFα can induce MAPK9. MAPK9 play a main role in the regulation of regional specific apoptosis during early brain development and providing protection against autoimmune diabetes.
Applications : Kinase Assay, Western Blot
Molecular Weight : 70 kDa
Expression System : Sf9 insect cells using baculovirus.
Species : Human
Form : Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.25 mM DTT, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
Specific Activity : 3.3 nmol/min/mg
Purity : > 95 %
Concentration : 0.1 ug/ul
Sequences : Full-length
Storage : Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Pathways : Adipocytokine signaling pathway; Colorectal cancer; Epithelial cell signaling in Helicobacter pylori infection; ErbB signaling pathway; Fc epsilon RI signaling pathway; Focal adhesion; GnRH signaling pathway; Insulin signaling pathway; MAPK signaling pathway; Neurotrophin signaling pathway; Pancreatic cancer; Pathways in cancer; RIG-I-like receptor signaling pathway; T cell receptor signaling pathway; Toll-like receptor signaling pathway; Type II diabetes mellitus; Wnt signaling pathway
Rendering based on PDB3E7O. :

Gene Name : MAPK9 mitogen-activated protein kinase 9 [ Homo sapiens ]
Official Symbol : MAPK9
Synonyms : MAPK9; JNK2; SAPK; p54a; JNK2A; JNK2B; PRKM9; JNK-55; JNK2BETA; p54aSAPK; JNK2ALPHA; Jun kinase; MAP kinase 9; c-Jun kinase 2; c-Jun N-terminal kinase 2; stress-activated protein kinase JNK2; mitogen-activated protein kinase 9 isoform JNK2 alpha2; mitogen-activated protein kinase 9; EC; Mitogen-activated protein kinase 9; Stress-activated protein kinase JNK2; OTTHUMP00000161542; OTTHUMP00000161543
Gene ID : 5601
mRNA Refseq : NM_139068
Protein Refseq : NP_620707
MIM : 602896
UniProt ID : P45984
Chromosome Location : 5q35
Function : ATP binding; JUN kinase activity; MAP kinase activity; kinase activity; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity

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