Recombinant Human Mitogen-activated Protein Kinase-Activated Protein Kinase 3, GST-tagged
Cat.No. : | MAPKAPK3-1055H |
Product Overview : | Recombinant full-length human MAPKAPK3 was expressed in E. coli cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | MAPKAPK3-1055H |
Description : | MAPKAPK3 is closely related to MAPKAPK2 sharing 72% nucleotide and 75% amino acid identity. MAPKAPK3 is activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of MAPKAPK3 as an integrative element of signaling in both mitogen and stress responses. |
Applications : | Kinase Assay; Western Blot |
Molecular Weight : | 69 kDa |
Expression System : | E. coli |
Species : | Human |
Form : | Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. |
Purity : | > 90% |
Concentration : | 0.2 ug/ul |
Sequences : | Full-length |
Storage : | Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Pathways : | Activated TLR4 signalling; FAS pathway and Stress induction of HSP regulation; Immune System; MAP kinase activation in TLR cascade; MAPK signaling pathway; MyD88 cascade initiated on plasma membrane; MyD88 dependent cascade initiated on endosom; MyD88:Mal cascade initiated on plasma membrane; NFkB and MAP kinases activation mediated by TLR4 signaling repertoire; NGF signalling via TRKA from the plasma membrane; Signaling mediated by p38-alpha and p38-beta; Signalling by NGF |
Gene Name : | MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 [ Homo sapiens ] |
Official Symbol : | MAPKAPK3 |
Synonyms : | MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3; 3PK; MAPKAP3; MAPKAPK-3; MAP kinase-activated protein kinase 3; MAPKAP kinase 3; OTTHUMP00000210805; OTTHUMP00000210806; OTTHUMP00000210807; chromosome 3p kinase; MAPK-activated protein kinase 3; EC 2.7.11.1 |
Gene ID : | 7867 |
mRNA Refseq : | NM_004635 |
Protein Refseq : | NP_004626 |
MIM : | 602130 |
UniProt ID : | Q16644 |
Chromosome Location : | 3p21.3 |
Function : | ATP binding; MAP kinase kinase activity; nucleotide binding; protein binding; protein serine/threonine kinase activity |
Products Types
◆ Recombinant Protein | ||
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Mapkapk3-216M | Recombinant Mouse Mapkapk3 Protein, MYC/DDK-tagged | +Inquiry |
MAPKAPK3-551H | Recombinant Human MAPKAPK3 Protein, MYC/DDK-tagged | +Inquiry |
MAPKAPK3-2494R | Recombinant Rhesus Macaque MAPKAPK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAPKAPK3-1230H | Recombinant Human MAPKAPK3 Protein (D2-Q382), GST tagged | +Inquiry |
◆ Lysates | ||
MAPKAPK3-723HCL | Recombinant Human MAPKAPK3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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