Recombinant Human Protein Arginine Methyltransferase 3, GST-tagged
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Cat. No. : | PRMT3-1617H |
Product Overview : | Recombinant full-length human PRMT3 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
Description : | PRMT3 is a protein arginine methyltransferase that catalyze the formation of asymmetric N (G),N (G)-dimethylarginine (ADMA) residues in proteins. 40S ribosomal protein S2 is a physiological substrate of PRMT3 and PRMT3 regulates ribosome biosynthesis at a stage beyond pre-rRNA processing. DAL-1 (differentially expressed in adenocarcinoma of the lung)/4.1B is a tumor suppressor gene that can significantly inhibits PRMT3 methylation of cellular substrates. Modulation of post-translational methylation may be an important mechanism through which DAL-1/4.1B affects tumor cell growth. |
Applications : | Western Blot |
Molecular Weight : | 97 kDa |
Expression System : | Sf9 insect cells using baculovirus |
Species : | Human |
Form : | Recombinant protein stored in 50 mM Tris-HCL, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol, 0.1 mM EDTA. |
Purity : | > 90 % |
Concentration : | 0.1 ug/ul |
Storage : | Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | PRMT3 protein arginine methyltransferase 3 [ Homo sapiens ] |
Official Symbol : | PRMT3 |
Synonyms : | PRMT3; protein arginine methyltransferase 3; HRMT1L3; HMT1 hnRNP methyltransferase-like 3 (S. cerevisiae); Protein arginine N-methyltransferase 3; EC 2.1.1;Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3 |
Gene ID : | 10196 |
mRNA Refseq : | NM_001145166 |
Protein Refseq : | NP_001138638 |
MIM : | 603190 |
UniProt ID : | O60678 |
Chromosome Location : | 11p15.1 |
Function : | metal ion binding; protein-arginine N-methyltransferase activity; transferase activity; zinc ion binding |
◆ Recombinant Protein
PRMT3-097H | Recombinant Human PRMT3 Protein, GST-tagged | +Inquiry |
PRMT3-007H | Recombinant Human PRMT3 Protein, GST-tagged | +Inquiry |
PRMT3-3003H | Recombinant Human PRMT3 Protein, MYC/DDK-tagged | +Inquiry |
Prmt3-5132M | Recombinant Mouse Prmt3 Protein, Myc/DDK-tagged | +Inquiry |
PRMT3-5042H | Recombinant Human PRMT3 Protein, GST-tagged | +Inquiry |
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◆ Assay kits
Kit-1856 | PRMT3 Homogeneous Assay Kit | +Inquiry |
Kit-1855 | PRMT3 Chemiluminescent Assay Kit | +Inquiry |
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