"SMYD2" Related Products

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Recombinant Human SET And MYND Domain Containing 2, GST-tagged

Cat. No.: SMYD2-1633H
Product Overview: Recombinant full-length human SMYD2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: SMYD2 (also known as SET and MYND domain-containing protein 2) is a member of the SMYD family of protein methyltransferases. SMYD2 is also known as lysine methyltransferase protein 3C (KMT3C). SMYD2 functions to repress transcription by interacting with the Sin3A histone deacetylase complex and performs methylation of Lys36 in histone H3. The exogenous expression of SMYD2 in mouse fibroblasts decreases cell growth. SMYD2 also function as a putative oncogene by methylating p53 and repressing its tumor suppressive function.
Applications: Western Blot
Molecular Weight: 70 kDa
Expression System: Sf9 insect cells using baculovirus
Species: Human
Form: Recombinant protein stored in 50 mM Tris-HCL, pH 7.5, 150 mM NaCl, 0.1 mM PMSF, 0.25 mM DTT, 10 mM gluthione, 0.1 mM EDTA, 25 % glycerol.
Purity: > 85 %
Concentration: 0.1 ug/ul
Sequences: Full-length
Storage: Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: SMYD2 SET and MYND domain containing 2 [ Homo sapiens ]
Official Symbol: SMYD2
Synonyms: SMYD2; SET and MYND domain containing 2; KMT3C; HSKM-B; ZMYND14; MGC119305; zinc finger, MYND domain containing 14; OTTHUMP00000035134; Lysine N-methyltransferase 3C
Gene ID: 56950
mRNA Refseq: NM_020197
Protein Refseq: NP_064582
MIM: 610663
UniProt ID: Q9NRG4
Chromosome Location: 1q32.3-q41
Function: metal ion binding; protein binding; zinc ion binding

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