"SRMS" Related Products

Recombinant Human Src-Related Kinase Lacking C-terminal Regulatory Tyrosine And N-terminal Myristylation Sites, GST-tagged

Cat. No.: SRMS-1101H
Product Overview: Recombinant human SRMS (215-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: SRMS is a Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites that is involved in proliferation or differentiation of keratinocytes in the skin. SRMS functions as a rapid downstream signaling intermediate following calcium-induced differentiation in keratinocytes. SRMS constitutes a new family of non-receptor tyrosine kinases that may be redundant in function. SRMS can act either in the membrane or at the nucleus, and may change localization patterns depending on external stimuli.
Applications: Kinase Assay; Western Blot
Molecular Weight: 54 kDa
Expression System: Sf9 insect cells using baculovirus
Species: Human
Form: Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol.
Specific Activity: 24 nmol/min/mg
Purity: > 95 %
Concentration: 0.1 ug/ul
Sequences: 215-end
Storage: Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name: SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites [ Homo sapiens ]
Official Symbol: SRMS
Synonyms: SRMS; src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites; SRM; C20orf148; dJ697K14.1; tyrosine-protein kinase Srms; EC 2.7.10.2; chromosome 20 open reading frame 148
Gene ID: 6725
mRNA Refseq: NM_080823
Protein Refseq: NP_543013
UniProt ID: Q9H3Y6
Chromosome Location: 20
Function: ATP binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; protein binding; transferase activity

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