Recombinant Human TAO Kinase 3, GST-tagged

• Cat.No.: TAOK3-1110H
• Product Overview: Recombinant human TAOK3 (1-463) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Cat. No.: TAOK3-1110H
• Description: TAOK3 or TAO kinase 3 is a member of the serine/threonine-protein kinase family that inhibits the basal activity of Jun kinase and is negatively regulated by epidermal growth factor (EGF). Overexpression of TAOK3 may activate the ERK1/ERK2 and JNK/SAPK targets. TAOK3 is highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
• Applications: Kinase Assay; Western Blot
• Molecular Weight: 89 kDa
• Expression System: Sf9 insect cells using baculovirus
• Species: Human
• Form: Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol.
• Specific Activity: 260 nmol/min/mg
• Purity: > 90 %
• Concentration: 0.1 ug/ul
• Sequences: Full-length
• Storage: Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Pathways: MAPK signaling pathway

Gene Information

• Gene Name: TAOK3 TAO kinase 3 [ Homo sapiens ]
• Official Symbol: TAOK3
• Synonyms: TAOK3; TAO kinase 3; DPK; JIK; MAP3K18; FLJ31808; DKFZp666H245; serine/threonine-protein kinase TAO3; hKFC-A; STE20-like kinase; JNK/SAPK-inhibitory kinase; jun kinase-inhibitory kinase; kinase from chicken homolog A; CTCL-associated antigen HD-CL-09; dendritic cell-derived protein kinase; thousand and one amino acid protein 3; cutaneous T-cell lymphoma-associated antigen HD-CL-09; EC 2.7.11.1
• Gene ID: 51347
• mRNA Refseq: NM_016281
• Protein Refseq: NP_057365
• UniProt ID: Q9H2K8
• Chromosome Location: 12q
• Function: ATP binding; nucleotide binding; protein kinase inhibitor activity; protein serine/threonine kinase activity; transferase activity