"TTBK2" Related Products

Recombinant Human Tau Tubulin Kinase 2, GST-tagged

Cat. No.: TTBK2-1114H
Product Overview: Recombinant mouse TTBK2 (70-538) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description: TTBK2 or tau tubulin kinase 2 is a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. TTBK2 is a member of the casein kinase (CK1) group of eukaryotic protein kinases that is involved in tau phosphorylation and aggregation. Mutations in TTBK2 cause spinocerebellar ataxia type 11 (SCA11) (a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem).
Applications: Kinase Assay; Western Blot
Molecular Weight: 88kDa
Expression System: Sf9 insect cells using baculovirus
Species: Human
Form: Recombinant protein stored in 50mM Tris-HCI, pH 7.5, 150mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1mM PMSF, 25% glycerol.
Specific Activity: 370nmol/min/mg
Purity: >95%
Concentration: 0.1 ug/ul
Sequences: 27-end
Storage: Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. Product shipped on dry ice.
Gene Name: TTBK2 tau tubulin kinase 2 [ Homo sapiens ]
Official Symbol: TTBK2
Synonyms: TTBK2; tau tubulin kinase 2; TTBK; SCA11; KIAA0847; spinocerebellar ataxia 11; NP_775771.3; EC 2.7.11.1; tau-tubulin kinase; EC 2.7.11
Gene ID: 146057
mRNA Refseq: NM_173500
Protein Refseq: NP_775771
MIM: 611695
UniProt ID: Q6IQ55
Chromosome Location: 15q15.2
Function: ATP binding; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity

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