"VRK1" Related Products


Recombinant Human Vaccinia Related Kinase 1, GST-tagged

Cat. No. : VRK1-1117H
Product Overview : Recombinant full-length human VRK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : VRK1 is a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. VRK1 is widely expressed in human tissues and actively dividing cells, such as those in testis, leukocytes, fetal liver and carcinomas. VRK1 regulate cell proliferation and phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. The spinal muscular atrophy with pontocerebellar hypoplasia is caused by a mutation in the VRK1 gene.
Applications : Kinase Assay; Western Blot
Molecular Weight : 71 kDa
Expression System : Sf9 insect cells using baculovirus
Species : Human
Form : Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25 % glycerol.
Purity : > 95 %
Concentration : 0.1 ug/ul
Sequences : Full-length
Storage : Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Gene Name : VRK1 vaccinia related kinase 1 [ Homo sapiens ]
Official Symbol : VRK1
Synonyms : VRK1; vaccinia related kinase 1; PCH1; MGC117401; MGC138280; MGC142070; serine/threonine-protein kinase VRK1; vaccinia-related kinase 1; vaccinia virus B1R-related kinase 1; EC
Gene ID : 7443
mRNA Refseq : NM_003384
Protein Refseq : NP_003375
MIM : 602168
UniProt ID : Q99986
Chromosome Location : 14q32
Function : ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity

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