Recombinant Human Proteasome (prosome, macropain) Subunit, Beta Type, 2, His-tagged
Cat.No. : | PSMB2-1321H |
Product Overview : | Recombinant human PSMB2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
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Cat. No. : | PSMB2-1321H |
Description : | PSMB2 is a member of the proteasome T1B family, which is a 20S core beta subunit. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 30% glycerol, 0.1 M NaCl. |
Molecular Weight : | 24.9 kDa (221 aa) confirmed by MALDI-TOF |
Purity : | >90 % by SDS-PAGE |
Concentration : | 0.5 mg/ml (determined by Bradford assay) |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MEYLIGIQGP DYVLVASDRV AASNIVQMKD DHDKMFKMSE KILLLCVGEA GDTVQFAEYI QKNVQLYKMR NGYELSPTAA ANFTRRNLAD CLRSRTPYHV NLLLAGYDEH EGPALYYMDY LAALAKAPFA AHGYGAFLTL SILDRYYTPT ISRERAVELL RKCLEELQKR FILNLPTFSV RIIDKNGIHD LDNISFPKQG S |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | APC/C-mediated degradation of cell cycle proteins; Adaptive Immunity Signaling; Antigen processing; Apoptosis; Assembly of the pre-replicative complex; Autodegradation of the E3 ubiquitin ligase COP1; Cell Cycle Checkpoints; DNA Replication; G1/S DNA Damage Checkpoints; HIV Infection; G1/S Transition; Immune System; Immunoproteasome; Metabolism of RNA |
Gene Name : | PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 [ Homo sapiens ] |
Official Symbol : | PSMB2 |
Synonyms : | PSMB2; proteasome (prosome, macropain) subunit, beta type, 2; HC7-I; MGC104215; MGC126885; proteasome subunit beta type-2; OTTHUMP00000004345; macropain subunit C7-I; proteasome beta 2 subunit; proteasome component C7-I; proteasome subunit, beta type, 2; multicatalytic endopeptidase complex subunit C7-1; multicatalytic endopeptidase complex subunit C7-I; NP_001186708.1; EC 3.4.25.1 |
Gene ID : | 5690 |
mRNA Refseq : | NM_001199779 |
Protein Refseq : | NP_001186708 |
MIM : | 602175 |
UniProt ID : | Q59FJ0 |
Chromosome Location : | 1p34.2 |
Function : | peptidase activity; threonine-type endopeptidase activity |
Products Types
◆ Recombinant Protein | ||
PSMB2-4430R | Recombinant Rat PSMB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Psmb2-5179M | Recombinant Mouse Psmb2 Protein, Myc/DDK-tagged | +Inquiry |
PSMB2-3474R | Recombinant Rhesus Macaque PSMB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
PSMB2-31209TH | Recombinant Human PSMB2, His-tagged | +Inquiry |
PSMB2-3656R | Recombinant Rhesus monkey PSMB2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PSMB2-2774HCL | Recombinant Human PSMB2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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