Recombinant Human Hexamethylene Bis-Acetamide Inducible 1, His-tagged
Cat.No. : | HEXIM1-5019H |
Product Overview : | Recombinant HEXIM1 protein was expressed in E. coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | HEXIM1-5019H |
Description : | HEXIM1 is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This protein has been shown to form a protein-RNA complex composed of 7SK small nuclear RNA and positive transcription elongation factor b (P-TEFb), which is composed of cyclin-dependent kinase 9 (CDK9) and cyclin T1, and to inhibit the kinase activity of CDK9, thereby suppressing RNA polymerase II-dependent transcriptional elongation. |
Concentration : | 0.5 mg/ml |
Source : | Human |
Host : | E.coli |
Form : | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol and 0.1M NaCl. |
Purity : | > 90% by SDS - PAGE |
Sequence : | 1-359 amino acids: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMAE PFLSEYQHQP QTSNCTGAAA VQEELNPERP PGAEERVPEE DSRWQSRAFP QLGGRPGPEG EGSLESQPPP LQTQACPESS CLREGEKGQN GDDSSAGGDF PPPAEVEPTP EAELLAQPCH DSEASKLGAP AAGGEEEWGQ QQRQLGKKKH RRRPSKKKRH WKPYYKLTWE EKKKF |
Molecular Mass : | 44.8 kDa (396aa), confirmed by MALDI-TOF. |
Applications : | SDS-PAGE |
Storage : | Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Gene Name : | HEXIM1 hexamethylene bis-acetamide inducible 1 [ Homo sapiens ] |
Official Symbol : | HEXIM1 |
Synonyms : | hexamethylene bis-acetamide inducible 1; CLP1; EDG1; HIS1; MAQ1; FLJ13562; HEXIM1; protein HEXIM1; HMBA-inducible ; menage a quatre 1; cardiac lineage protein 1; menage a quatre protein 1; estrogen down-regulated gene 1 protein; hexamthylene bis-acetamide inducible 1; hexamethylene bisacetamide-inducible protein; hexamethylene bis-acetamide-inducible protein 1; hexamethylene-bis-acetamide-inducible transcript 1; CLP-1; HMBA-inducible; Estrogen down-regulated gene 1 protein; Cardiac lineage protein 1; Menage a quatre protein 1; Hexamethylene bis-acetamide-inducible protein 1 |
Gene ID : | 10614 |
mRNA Refseq : | NM_006460 |
Protein Refseq : | NP_006451 |
MIM : | 607328 |
UniProt ID : | O94992 |
Chromosome Location : | 17q21.31 |
Function : | cyclin-dependent protein kinase inhibitor activity; protein binding; snRNA binding; specific transcriptional repressor activity; transcription repressor activity |
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HEXIM1-150H | Active Recombinant Human HEXIM1 Protein | +Inquiry |
HEXIM1-2490R | Recombinant Rat HEXIM1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
HEXIM1-5577HCL | Recombinant Human HEXIM1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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