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Active Recombinant Mouse Car10, His-tagged

Cat.No. : Car10-1805M
Product Overview : A DNA sequence encoding the mouse Car10 (Met 1-Asn 300) was expressed, fused with a C-terminal polyhistidine tag.
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Description : Carbonic anhydrase X, also called carbonic anhydrase - related protein X (CARPX) and CA10, belongs to the CA family of zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide in various biological processes such as respiration, renal tubular acidification and bone resorption. The secreted protein CARPX without CA activity (hydration of CO2) is identified as an acatalytic member of the alpha-carbonic anhydrase subgroup. CARP X expression is detected in the adult total brain and almost all parts of the central nervous system, but not in the fetal brain. Accordingly, CARP X is suggested to play a role in the development of central nervous system, especially the brain. The same CARP X protein are encoded by multiple transcript variants of this gene.
Source : Human Cells
Species : Mouse
Tag : His
Predicted N Terminal : Gln 23
Form : Lyophilized from sterile 25mM Tris, 150mM NaCl, pH 7.4
Bio-activity : Measured by its esterase activity. The specific activity is >10 pmoles/min/μg.
Molecular Mass : The secreted recombinant mouse Car10 comprises 289 amino acids and has a calculated molecular mass of 33.1 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 38 kDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >97 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70℃
Storage : Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : A hardcopy of COA with reconstitution instruction is sent along with the products.?
Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Gene Name : Car10?carbonic anhydrase 10 [?Mus musculus?(house mouse) ]
Official Symbol : Car10
Synonyms : Car10; Ca10; BB085816; 2700029L05Rik; carbonic anhydrase 10; carbonic anhydrase-related protein 10; CARP X; CA-RP X; carbonic anhydrase-related protein X
Gene ID : 72605
mRNA Refseq : NM_028296
Protein Refseq : NP_082572
UniProt ID : P61215
Chromosome Location : 11; 11 C
Function : molecular_function

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the tissue-specific expression pattern of CA10 protein? 12/18/2022

CA10 protein is primarily expressed in the kidneys and brain.

What is the role of CA10 protein in intracellular pH regulation? 04/07/2021

CA10 protein contributes to intracellular pH regulation.

How does CA10 protein's enzymatic activity compare to other carbonic anhydrases? 03/29/2021

CA10 protein's enzymatic activity varies compared to other carbonic anhydrases, and further research is needed to identify its specific substrates and catalytic mechanisms.

Can genetic models be developed to study CA10 protein's cellular roles? 03/26/2018

Yes, genetic models like knockouts can be developed to study CA10 protein's cellular functions and associated phenotypic changes.

What are the primary tissues expressing CA10 protein? 12/25/2017

CA10 protein is primarily expressed in the kidneys and brain.

What post-translational modifications regulate CA10 protein's activity and stability? 09/04/2017

The specific post-translational modifications governing CA10 protein's activity and stability are under investigation.

Are there known disease associations with CA10 protein? 07/07/2016

There are currently no widely reported disease associations or implications related to CA10 protein.

Customer Reviews (3)

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Reviews
08/26/2022

    Accurate protein characterization, facilitates data interpretation.

    08/05/2021

      Dependable quantification, ensures data accuracy.

      11/03/2020

        Expert support, indispensable for our protein experiments.

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