"IL4" Related Products

Recombinant Murine Interleukin-4

Cat. No.: Il4-11M
Product Overview: Recombinant murine IL-4 produced inE.coliis a 13.5kDa globular protein containing 120 amino acid residues.
Description: IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and alergy.
Purity: >95% as determined by SDS-PAGE.
Formulation: Sterile filtered lyophilized powder
Specific Activity: The ED50 was determined by the dose-dependent proliferation of murine HT-2 cells is < 2.0ng/ml, corresponding to a specific activity of > 5 x 105IU/mg.
Endotoxin: Less than 0.1ng/µg (1 IEU/µg) determined by LAL test.
Reconstitution: It is recommended to reconstitute the lyophilized rmIL-4 in sterile 18MΩ-H2O containing at least 0.1% human serum albumin or bovine serum albumin to prepare a stock solution of no less than 5μg/ml of the cytokine.
Storage: Lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted murine IL-4 should be stored in working aliquots at -20°C. Aliquot to avoid repeated freeze-thaw cycles.
Gene Name: Il4
Synonyms: BSF1; IL-4; BCGF1; BCGF-1; MGC79402; BCGF, BCDF, B cell stimulating factor 1, Lymphocyte stimulatory factor 1, Binetrakin, Pitrakinra, Interleukin-4, IGG1 induction factor, B-cell IgG differentiation factor; Interleukin-4 Precursor; IL-4;BSF-1;B-cell growth factor 1
Gene ID: 16189
mRNA Refseq: NM_021283
Protein Refseq: NP_067258
UniProt ID: Q5SV00; P07750
Chromosome Location: 11 B1.3; 11 29.0 cM
Pathway: Cytokine-cytokine receptor interaction ; Fc epsilon RI signaling pathway ; Hematopoietic cell lineage ; Jak-STAT signaling pathway ; T cell receptor signaling pathway
Function: interleukin-4 receptor binding; protein binding

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.