||Recombinant Human CD-4 produced in Escherichia Coli encodes amino acids 203-317and fused to His Tag protein.
||CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.
||Sterile lyophilized powder.
||Each mg contains 1X PBS, 0.1% SDS and 1mM DTT.
|Application and Suggested Dilutions:
||• Protein Assay • Antibody Production • Western Blotting
||Store vial at -20oC to -80oC. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.