||Recombinant Human WW DomainBinding Protein 1/WBP1 produced by E. coli expression system. The target protein is expressed with sequence (Gly170Pro269) of Human WBP1 fused with a 6His tag at the Nterminus and the Cterminus.
||WW DomainBinding Protein 1 (WBP1) is widely expressed in many tissues, but it is lowly expressed in the lung, placenta, kidney, and liver. WBP1 contains two WWbinding motifs: WWbinding 1 and WWbinding 2 that are involved in mediating proteinprotein interactions through the binding of polyproline ligands. The WWbinding domain is composed of 38 to 40 semiconserved amino acids shared by proteins with diverse functions including structural, regulatory, and signaling proteins. In addition, WBP1 also encodes a ligand of the WW domain of the Yes kinaseassociated protein. This function has not been determined.
||Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.4
||Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
||For research use only.
||Lyophilized protein should be stored at less than 20°C. though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C. for 2-7 days.Aliquots of reconstituted samples are stable at less than 20°C. for 3 months.