Native Human Serum Alpha 1-AntiChymoTrypsin

• Cat.No.: SERPINA3-8008H
• Product Overview: Human Serum Alpha 1-AntiChymoTrypsin was purified from Human Serum.

Specification

• Description: Human Alpha 1 antichymotrypsin (Alpha 1-ACT) (ACT)is an alpha globulin glycoprotein and serpin. This Human Glycoprotein is found in alpha(1)-globulin region in human serum. Human Alpha 1-antichymotrypsin (ACT)(Alpha 1-ACT) inhibits chymotrypsin-like proteinases in vivo and has cytotoxic killer-cell activity in vitro. Human Alpha 1-antichymotrypsin (ACT)(Alpha 1-ACT) also has a role as an acute-phase protein and is active in the control of immunologic and inflammatory processes, and as a tumor marker. Human Alpha 1-antichymotrypsin (ACT)(Alpha 1-ACT) is a member of the serpin superfamilyHuman Alpha 1-antichymotrypsin (Alpha 1-ACT) (ACT)can complex with human PSA to form human PSA-ACT complex which is used as an indicator of tumour mass and clinical stage of prostate cancer
• Source: Human Serum
• Species: Human
• Form: Lyophilized from 0.02M Tris buffer, pH 7.5 containing 0.15M NaCl
• Molecular Mass: 68 kDa
• Purity: >90% by SDS-PAGE
• Stability: 2 years
• Storage: 2-8 °C

Gene Information

• Gene Name: SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 [ Homo sapiens ]
• Official Symbol: SERPINA3
• Synonyms: SERPINA3; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; AACT, alpha 1 antichymotrypsin , serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 3; alpha-1-antichymotrypsin
• Gene ID: 12
• mRNA Refseq: NM_001085
• Protein Refseq: NP_001076
• MIM: 107280
• UniProt ID: P01011
• Chromosome Location: 14q32.1
• Pathway: Selenium Pathway, organism-specific biosystem
• Function: DNA binding; peptidase inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity