Native Human CKB protein


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Native Human CKB protein

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Cat.No. : CKB-8079H
Product Overview : Native Human CKB was purified in Human Brain.
Description : The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized.
Source : Human Brain
Species : Human
Form : 50% Glycerol, 25 mM Imidazole, 1 mM DTE, pH 6.5.
Bio-activity : > 500 U/mL (Dimension® Clinical Chemistry System)
Unit Definition : One unit will transfer one micromole of phosphate from creatine phosphate to ADP per minute at 37 centigrade
Storage : Store at -20 centigrade.
Concentration : > 0.5 mg protein/mL (Coomassie)
Gene Name : CKB creatine kinase, brain [ Homo sapiens ]
Official Symbol : CKB
Synonyms : CKB; creatine kinase, brain; CKBB; creatine kinase B-type; creatine kinase-B; creatine kinase B chain; B-CK;
Gene ID : 1152
mRNA Refseq : NM_001823
Protein Refseq : NP_001814
MIM : 123280
UniProt ID : P12277
Chromosome Location : 14q32.32
Pathway : Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Creatine metabolism, organism-specific biosystem; Creatine pathway, organism-specific biosystem; Creatine pathway, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Function : ATP binding; creatine kinase activity; nucleotide binding;

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