Native Human Eosinophil Peroxidase

• Cat.No.: EPX-8107H
• Product Overview: Human Eosinophil Peroxidase was purified from Human Eosinophils.

Specification

• Description: This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded precursor protein is processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a cluster of three peroxidase genes at chromosome 17q23. Mutations in this gene result in eosinophil peroxidase deficiency.
• Source: Human Eosinophils
• Species: Human
• Form: Liquid - Phosphatse and Sodium Chloride buffer pH 7.5
• Molecular Mass: 77 kDa
• Purity: Typically >98% by SDS-PAGE
• Storage: 2-8 °C
• Concentration: Typically >0.5 mg protein/mL

Gene Information

• Gene Name: EPX eosinophil peroxidase [ Homo sapiens ]
• Official Symbol: EPX
• Synonyms: EPX; eosinophil peroxidase; EPO; EPP; EPX PEN; EPX-PEN
• Gene ID: 8288
• mRNA Refseq: NM_000502
• Protein Refseq: NP_000493
• MIM: 131399
• UniProt ID: P11678
• Chromosome Location: 17q23.1
• Pathway: Asthma, organism-specific biosystem; Asthma, conserved biosystem
• Function: heme binding; metal ion binding; oxidoreductase activity; peroxidase activity