Native E.coli ung

• Cat.No.: ung-8332E
• Product Overview: E.coli Uracil DNA Glycosilase (UNG) catalyses the release of free Uracil from Uracil-containing DNA. UNG efficiently hydrolyzes uracil from signle-stranded or double-stranded DNA, but not from oligomers (6 fewer bases).

Specification

• Description: UDG and Ndk form a complex (Goswami, 2006). Uracil can be generated in DNA as a result of misincorporation by DNA polymerase, spontaneous deamination of cytosine, and deamination of cytosine induced by bisulfite or nitrous acid.
• Source: E.coli
• Species: E.coli
• Form: 10mM Tris-Hcl (pH-7.4 at 25C), 50mM KCl, 1mM DTT, 0.1mM EDTA, 0.1 mg/ml BSA and 50% glycerol.
• Notes: For research use only.
• Storage: Uracil DNA Glycosilase although stable at 15°C for week, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles.

Gene Information

• Gene Name: ung uracil-DNA-glycosylase [ Escherichia coli str. K-12 substr. MG1655 ]
• Official Symbol: ung
• Synonyms: ECK2578; JW2564
• Gene ID: 947067
• Protein Refseq: NP_417075
• Pathway: Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem