Recombinant Human MAOB, His tagged

• Cat.No.: MAOB-8316H
• Product Overview: MAO-B Human Recombinant produced in E.coli is a single, non-glycosylated, Polypeptide chain containing 488 amino acids fragment (2-489) corresponding to the cytoplasmic domain fragment of the mature protein, having total molecular mass of 62kDa and fused with 4.5kDa amino-terminal hexahistidine tag. The MAO-B is purified by chromatographic techniques.

Specification

• Description: The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine.
• Source: E.coli
• Species: Human
• Tag: His
• Form: MAO-B protein is supplied in 1x PBS and 50% glycerol.
• Purity: Greater than 95.0% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Store at 4 ℃ if entire vial will be used within 2-4 weeks. Store frozen at -20 ℃ for longer periods of time. Please avoid freeze/thaw cycles.

Gene Information

• Gene Name: MAOB monoamine oxidase B [ Homo sapiens ]
• Official Symbol: MAOB
• Synonyms: MAOB; monoamine oxidase B; amine oxidase [flavin-containing] B; MAO-B; MAO, brain; MAO, platelet; tyramine oxidase; adrenalin oxidase; monoamine oxidase type B; MGC26382
• Gene ID: 4129
• mRNA Refseq: NM_000898
• Protein Refseq: NP_000889
• MIM: 309860
• UniProt ID: P27338
• Chromosome Location: Xp11.4-p11.3
• Pathway: Alpha-synuclein signaling, organism-specific biosystem; Amine Oxidase reactions, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Biological oxidations, organism-specific biosystem
• Function: electron carrier activity; flavin adenine dinucleotide binding; oxidoreductase activity; primary amine oxidase activity; protein homodimerization activity