Recombinant Human TOMM20, His-tagged

• Cat.No.: TOMM20-7601H
• Product Overview: Recombinant human TOMM20 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: Mmitochondrial import receptor subunit TOMM20 homolog, also known as TOMM20, belongs to the Tom20 family. The Tom machinery consists of import receptors for the initial binding of cytosolically synthesized preproteins and a general import pore (GIP) for the membrane translocation of various preproteins into the mitochondria. TOMM20 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 2mM DTT
• Molecular Mass: 16.2kDa (144aa)
• Protein length: 25-145aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSDRKRRSD PNFKNRLRER RKKQKLAKER AGLSKLPDLK DAEAVQKFFL EEIQLGEELL AQGEYEKGVD HLTNAIAVCG QPQQLLQVLQ QTLPPPVFQM LLTKLPTISQ RIVSAQSLAE DDVE
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) [ Homo sapiens ]
• Official Symbol: TOMM20
• Synonyms: TOMM20; translocase of outer mitochondrial membrane 20 homolog (yeast); mitochondrial import receptor subunit TOM20 homolog; KIAA0016; MAS20; MOM19; TOM20; translocase of outer mitochondrial membrane 20 homolog type II; mitochondrial 20 kDa outer membrane protein; outer mitochondrial membrane receptor Tom20; MGC117367
• Gene ID: 9804
• mRNA Refseq: NM_014765
• Protein Refseq: NP_055580
• MIM: 601848
• UniProt ID: Q15388
• Chromosome Location: 1q42
• Pathway: Metabolism of proteins, organism-specific biosystem; Mitochondrial Protein Import, organism-specific biosystem
• Function: P-P-bond-hydrolysis-driven protein transmembrane transporter activity; protein binding; unfolded protein binding