Recombinant Human AGTR2, GST-tagged

• Cat.No.: AGTR2-30H
• Product Overview: Recombinant Human AGTR2 (1 a.a. - 363 a.a.) fused with GST-tag at N-terminal, was expressed in wheat germ.

Specification

• Cat. No.: AGTR2-30H
• Description: The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
• Source: wheat germ
• Molecular Mass: 67.6 kDa
• Sequence: MKGNSTLATTSKNITSGLHFGLVNI SGNNESTLNCSQKPSDKHLDAIPIL YYIIFVIGFLVNIVVVTLFCCQKGP KKVSSIYIFNLAVADLLLLATLPLW ATYYSYRYDWLFGPVMCKVFGSFLT LNMFASIFFITCMSVDRYQSVIYPF LSQRRNPWQASYIVPLVWCMACLSS LPTFYFRDVRTIEYLGVNACIMAFP PEKYAQWSAGIALMKNILGFIIPLI FIATCYFGIRKHLLKTNSYGKNRIT RDQVLKMAAAVVLAFIICWLPFHVL TFLDALAWMGVINSCEVIAVIDLAL PFAILLGFTNSCVNPFLYCFVGNRF QQKLRSVFRVPITWLQGKRESMSCR KSSSLREMETFVS
• Storagebuffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
• Applications: ELISA; WB
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• OfficialSymbol: AGTR2

Gene Information

• Gene Name: AGTR2 angiotensin II receptor, type 2 [ Homo sapiens ]
• Synonyms: AGTR2; angiotensin II receptor, type 2; angiotensin receptor 2; type-2 angiotensin II receptor; AT2; MRX88; angiotensin II type-2 receptor; ATGR2
• Gene ID: 186
• mRNA Refseq: NM_000686
• Protein Refseq: NP_000677
• MIM: 300034
• UniProt ID: P50052
• Chromosome Location: Xq22-q23
• Pathway: ACE Inhibitor Pathway; Class A/1 (Rhodopsin-like receptors); GPCR downstream signaling
• Function: angiotensin type II receptor activity; protein binding; receptor antagonist activity