"AGTR2" Related Products

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Recombinant Human AGTR2, GST-tagged

Cat. No.: AGTR2-30H
Product Overview: Recombinant Human AGTR2 (1 a.a. - 363 a.a.) fused with GST-tag at N-terminal, was expressed in wheat germ.
Description: The protein encoded by this gene belongs to the G-protein coupled receptor 1 family, and functions as a receptor for angiotensin II. It is an intergral membrane protein that is highly expressed in fetus, but scantily in adult tissues, except brain, adrenal medulla, and atretic ovary. This receptor has been shown to mediate programmed cell death and this apoptotic function may play an important role in developmental biology and pathophysiology. Mutations in this gene are been associated with X-linked mental retardation.
Source: wheat germ
Molecular Mass: 67.6 kDa
Sequence: MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMETFVS
Storagebuffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Applications: ELISA; WB
Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
OfficialSymbol: AGTR2
Gene Name: AGTR2 angiotensin II receptor, type 2 [ Homo sapiens ]
Synonyms: AGTR2; angiotensin II receptor, type 2; angiotensin receptor 2; type-2 angiotensin II receptor; AT2; MRX88; angiotensin II type-2 receptor; ATGR2
Gene ID: 186
mRNA Refseq: NM_000686
Protein Refseq: NP_000677
MIM: 300034
UniProt ID: P50052
Chromosome Location: Xq22-q23
Pathway: ACE Inhibitor Pathway; Class A/1 (Rhodopsin-like receptors); GPCR downstream signaling
Function: angiotensin type II receptor activity; protein binding; receptor antagonist activity

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