Recombinant Human ODC1, GST-tagged

• Cat.No.: ODC1-2499H
• Product Overview: Recombinant Human ODC1 (1 a.a. - 461 a.a.) fused with GST-tag at N-terminal, was expressed in vitro wheat germ expression system.

Specification

• Cat. No.: ODC1-2499H
• Description: This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.
• Source: wheat germ
• Molecular Mass: 76.45 kDa
• Sequence: MNNFGNEEFDCHFLDEGFTAKDILD QKINEVSSSDDKDAFYVADLGDILK KHLRWLKALPRVTPFYAVKCNDSKA IVKTLAATGAGFDCASKTEIQLVQS LGVPPERIIYANPCKQVSQIKYAAN NGVQMMTFDSEVELMKVARAHPKAK LVLRIATDDSKAVCRLSVKFGATLR TSRLLLERAKELNIDVVGVSFHVGS GCTDPETFVQAISDARCVFDMGAEV GFSMYLLDIGGGFPGSEDVKLKFEE ITGVINPALDKYFPSDSGVRIIAEP GRYYVASAFTLAVNIIAKKIVLKEQ TGSDDEDESSEQTFMYYVNDGVYGS FNCILYDHAHVKPLLQKRPKPDEKY YSSSIWGPTCDGLDRIVERCDLPEM HVGDWMLFENMGAYTVAAASTFNGF QRPTIYYVMSGPAWQLMQQFQNPDF PPEVEEQDASTLPVSCAWESGMKRH RAACASASINV
• Purification: Glutathione Sepharose 4 Fast Flow
• Storage buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
• Applications: ELISA; WB
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Note: Best use within three months from the date of receipt of this protein.
• OfficialSymbol: ODC1

Gene Information

• Gene Name: ODC1 ornithine decarboxylase 1 [ Homo sapiens ]
• Synonyms: ODC1; ornithine decarboxylase 1; ornithine decarboxylase; ODC; EC 4.1.1.17
• Gene ID: 4953
• mRNA Refseq: NM_002539
• Protein Refseq: NP_002530
• MIM: 165640
• UniProt ID: P11926
• Chromosome Location: 2p25
• Pathway: Arginine and proline metabolism; Glutathione metabolism; Metabolism; Metabolism of amino acids and derivatives
• Function: ornithine decarboxylase activity