Active Recombinant SV40gp6, His-tagged
Cat.No. : | SV40gp6-8506S |
Product Overview : | Recombinant SV40gp6,fused with His tag, was expressed in Sf21 Cells. |
- Specification
- Gene Information
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Description : | The large T antigen (TAg) of Simian virus 40 acts as an initiator of DNA replication, participates in cellular transformation, and induces cell growth . A number of functional domains have been characterized including the N-terminal J domain, nuclear localization signal (NLS), internal helicase domain, Rb and topoisomerase I interacting domain, p53 and ATP binding domain . The p53-interacting domain is also essential for binding p300/CBP . Phosphorylation of TAg by several kinases may regulate its function both positively and negatively. |
Source : | Sf21 Cells |
Species : | Simian virus |
Tag : | His |
Form : | 20 mM Tris-Cl, pH 7.9, 20% Glycerol, 100 mM KCl, 1 mM DTT and 0.2 mM EDTA |
Bio-activity : | 1 unit equals 1 ng of purified protein. 50-500 units are sufficient for an in vitro unwinding assay and 100 units are sufficient for a protein-protein interaction assay. |
AA Sequence : | MDKVLNREES LQLMDLLGLE RSAWGNIPLM RKAYLKKCKE FHPDKGGDEE KMKKMNTLYK KMEDGVKYAH QPDFGGFWDA TEIPTYGTDE WEQWWNAFNE ENLFCSEEMP SSDDEATADS QHSTPPKKKR KVEDPKDFPS ELLSFLSHAV FSNRTLACFA IYTTKEKAAL LYKKIMEKYS VTFISRHNSY NHNILFFLTP HRHRVSAINN YAQKLCTFSF LICKGVNKEY LMYSALTRDP FSVIEESLPG GLKEHDFNPE EAEETKQVSW KLVTEYAMET KCDDVLLLLG MYLEFQYSFE MCLKCIKKEQ PSHYKYHEKH YANAAIFADS KNQKTICQQA VDTVLAKKRV DSLQLTREQM LTNRFNDLLD RMDIMFGSTG SADIEEWMAG VAWLHCLLPK MDSVVYDFLK CMVYNIPKKR YWLFKGPIDS GKTTLAAALL ELCGGKALNV NLPLDRLNFE LGVAIDQFLV VFEDVKGTGG ESRDLPSGQG INNLDNLRDY LDGSVKVNLE KKHLNKRTQI FPPGIVTMNE YSVPKTLQAR FVKQIDFRPK DYLKHCLERS EFLLEKRIIQ SGIALLLMLI WYRPVAEFAQ SIQSRIVEWK ERLDKEFSLS VYQKMKFNVA MGIGVLDWLR NSDDDDEDSQ ENADKNEDGG EKNMEDSGHE TGIDSQSQGS FQAPQSSQSV HDHNQPYHIC RGFTCFKKPP TPPPEPET |
Purity : | >95% as determined by SDS-PAGE |
Storage : | -80 °C |
Concentration : | 400 μg/ml |
Shipping : | Dry Ice |
Gene Name : | SV40gp6 large T antigen [ Simian virus 40 ] |
Official Symbol : | SV40gp6 |
Synonyms : | SV40gp6; large T antigen |
Gene ID : | 1489531 |
Protein Refseq : | YP_003708382 |
Products Types
◆ Recombinant Protein | ||
SV40gp6-1895S | Recombinant Simian Virus 40 Large T Antigen, His-tagged | +Inquiry |
◆ Native Protein | ||
SV40gp6-268 | Active Native Simian virus 40 SV40gp6 protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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