Recombinant Human APCS protein, His-tagged

• Cat.No.: APCS-8600H
• Product Overview: Recombinant Human APCS (His20-Val223) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).

Specification

• Description: Serum amyloid P-component (SAP) is also known as Pentraxin 2 (PTX2), APCS, which belongs to the pentaxin family. SAP contains one pentaxin domain. PTX2 is a secreted homopentamer protein which is found in serum and urine. SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. SAP can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. SAP may also function as a calcium-dependent lectin. SAP has certain sequence homology with C-reactive protein (CRP).
• Source: HEK293
• Species: Human
• Tag: His
• Predicted N Terminal: His20
• Form: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 24 kDa. The protein migrates as 26 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Protein length: His20-Val223
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: APCS
• Official Symbol: APCS
• Synonyms: APCS; amyloid P component, serum; serum amyloid P-component; 9.5S alpha 1 glycoprotein; MGC88159; pentaxin related; PTX2; SAP; pentaxin-related; 9.5S alpha-1-glycoprotein
• Gene ID: 325
• mRNA Refseq: NM_001639
• Protein Refseq: NP_001630
• MIM: 104770
• UniProt ID: P02743