Recombinant Human CPNE1 protein(Met1-Ala537), SUMO-tagged

• Cat.No.: CPNE1-8646H
• Product Overview: Recombinant Human CPNE1 (Q99829) (Met1-Ala537) was expressed in Insect Cells, fused with the SUMO tag at the N-terminus.

Specification

• Source: Insect Cells
• Species: Human
• Tag: N-SUMO
• Protein length: Met1-Ala537
• Form: Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.0, 10% gly Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The secreted recombinant human CPNE1 consists of 656 amino acids and predicts a molecular mass of 72.7 KDa. The apparent molecular mass of the protein is approximately 73 KDa in SDS-PAGE under reducing conditions due to glycosylation.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: CPNE1 copine I [ Homo sapiens ]
• Official Symbol: CPNE1
• Synonyms: CPNE1; copine I; copine-1; CPN1; COPN1; MGC1142
• Gene ID: 8904
• mRNA Refseq: NM_001198863
• Protein Refseq: NP_001185792
• MIM: 604205
• UniProt ID: Q99829

Reviews

07/08/2021

Reliable results, quality product.

03/15/2021

Worked great, fast shipping.

06/27/2020

Very happy with purchase.

Q&As

How does CPNE1 interact with calcium ions in cellular processes?

It binds to calcium ions, facilitating its interaction with phospholipids and proteins.

Are there known genetic alterations in CPNE1 associated with specific diseases?

Genetic alterations in CPNE1 have been associated with various types of cancer.

What role does CPNE1 play in the regulation of neuronal activity?

In neurons, CPNE1 is believed to play a role in synaptic function and plasticity.

What is the primary biological function of CPNE1?

CPNE1 is involved in calcium-dependent membrane interactions and cellular signaling.

In which tissues or cell types is CPNE1 predominantly expressed?

CPNE1 shows a broad expression pattern, including in neural and cancerous tissues.

How is CPNE1 implicated in cancer progression?

CPNE1 has been found to be upregulated in certain cancers, promoting tumor progression.

What research or therapeutic strategies are being explored involving CPNE1?

Research is focused on understanding its role in cancer, and it’s being explored as a potential therapeutic target.