Recombinant Human DIDO1, His-tagged

• Cat.No.: DIDO1-01H
• Product Overview: Recombinant Human DIDO1 protein, a DNA sequence encoding the full length Isoform 3 of DIDO1 corresponding to amino acid (1-562aa) was expressed with a C-terminal polyhistidine tag in Sf9.

Specification

• Description: Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.
• Source: Sf9 using a baculovirus expression system
• Species: Human
• Tag: His
• Form: PBS pH7.4
• Storage: Store it at +4℃ for short term. For long term storage, store it at -20℃ ~ -70℃ Avoid freeze/thaw cycles.

Gene Information

• Gene Name: DIDO1 death inducer-obliterator 1 [ Homo sapiens ]
• Official Symbol: DIDO1
• Synonyms: DIDO1; death inducer-obliterator 1; C20orf158, chromosome 20 open reading frame 158 , DATF1, death associated transcription factor 1; death-inducer obliterator 1; BYE1; DIO 1; DIO1; dJ885L7.8; FLJ11265; KIAA0333; death-associated transcription factor 1; DATF1; DIDO2; DIDO3; DIO-1; DATF-1; C20orf158; MGC16140; DKFZp434P1115
• Gene ID: 11083
• mRNA Refseq: NM_001193369
• Protein Refseq: NP_001180298
• MIM: 604140
• UniProt ID: Q9BTC0
• Chromosome Location: 20q13.33
• Pathway: Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Meiosis, organism-specific biosystem; Meiotic Synapsis, organism-specific biosystem
• Function: metal ion binding; zinc ion binding