"SH3GL2" Related Products

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Recombinant Human SH3GL2, His-tagged

Cat.No.: SH3GL2-15846H
Product Overview: Recombinant human SH3GL2 protein, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Description: SH3GL2 (SH3-domain GRB2-like 2), also known as endophilin-A1, belongs to the endophilin family. It contains a BAR domain and a SH3 domain. Members of the BAR domain protein superfamily are essential elements of cellular traffic. Endophilins are among the best studied BAR domain proteins. They have a prominent function in synaptic vesicle endocytosis (SVE), receptor trafficking and apoptosis, and in other processes that require remodeling of the membrane structure. SH3GL2 a novel tumor suppressor gene in laryngeal squamous cell carcinoma (LSCC), induces apoptosis of tumor cells by regulating intra-cellular signal transduction networks.
Source: E. coli
Species: Human
Tag: His
Form: Liquid. In 20 mM Tris-HCl buffer, pH8.0, 10% glycerol, 1mM DTT, 50mM NaCl
Molecular Mass: 42.5 kDa (376aa) confirmed by MALDI-TOF
Protein length: 1-352aa
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMSVAGL KKQFHKATQK VSEKVGGAEG TKLDDDFKEM ERKVDVTSRA VMEIMTKTIE YLQPNPASRA KLSMINTMSK IRGQEKGPGY PQAEALLAEA MLKFGRELGD DCNFGPALGE VGEAMRELSE VKDSLDIEVK QNFIDPLQNL HDKDLREIQHHLKKLEGRRL DFDYKKKRQG KIPDEELRQA LEKFDESKEI AESSMFNLLE MDIEQVSQLS ALVQAQLEYH KQAVQILQQV TVRLEERIRQ ASSQPRREYQ PKPRMSLEFP TGDSTQPNGG LSHTGTPKPS GVQMDQPCCR ALYDFEPENE GELGFKEGDI ITLTNQIDEN WYEGMLHGHSGFFPINYVEI LVALPH
Purity: >90% by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration: 1mg/ml (determined by Bradford assay)
Gene Name: SH3GL2 SH3-domain GRB2-like 2 [ Homo sapiens ]
Official Symbol: SH3GL2
Synonyms: SH3GL2; SH3-domain GRB2-like 2; endophilin-A1; CNSA2; EEN B1; SH3D2A; SH3P4; endophilin-1; SH3 domain protein 2A; Endophilin A1 BAR domain; bA335L15.1 (SH3-domain GRB2-like 2); SH3 domain-containing GRB2-like protein 2; EEN-B1; FLJ20276; FLJ25015;
Gene ID: 6456
mRNA Refseq: NM_003026
Protein Refseq: NP_003017
MIM: 604465
UniProt ID: Q99962
Chromosome Location: 9p22
Pathway: Axon guidance, organism-specific biosystem; Clathrin derived vesicle budding, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Disease, organism-specific biosystem; EGFR downregulation, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Endocytosis, organism-specific biosystem;
Function: identical protein binding; lipid binding; protein binding;

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