Recombinant Human AASDHPPT, GST-tagged

• Cat.No.: AASDHPPT-9200H
• Product Overview: Recombinant human AASDHPPT protein, fused to GST-tag, was expressed in E.coli and purified by GST-sepharose.

Specification

• Description: The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-309a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [ Homo sapiens ]
• Official Symbol: AASDHPPT
• Synonyms: AASDHPPT; aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; AASD PPT; CGI 80; LYS5; LYS5 ortholog; 4-phosphopantetheinyl transferase; alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; LYS2; CGI-80; AASD-PPT
• Gene ID: 60496
• mRNA Refseq: NM_015423
• Protein Refseq: NP_056238
• MIM: 607756
• UniProt ID: Q9NRN7
• Chromosome Location: 11q22
• Pathway: Metabolism, organism-specific biosystem; Metabolism of vitamins and cofactors, organism-specific biosystem; Metabolism of water-soluble vitamins and cofactors, organism-specific biosystem; Pantothenate and CoA biosynthesis, organism-specific biosystem; Pantothenate and CoA biosynthesis, conserved biosystem; Vitamin B5 (pantothenate) metabolism, organism-specific biosystem; acyl carrier protein metabolism, organism-specific biosystem
• Function: holo-[acyl-carrier-protein] synthase activity; magnesium ion binding; protein binding; transferase activity