Recombinant Human ABCB10, GST-tagged

• Cat.No.: ABCB10-9208H
• Product Overview: Recombinant human ABCB10 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 452-738a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 [ Homo sapiens ]
• Official Symbol: ABCB10
• Synonyms: ABCB10; ATP-binding cassette, sub-family B (MDR/TAP), member 10; ATP-binding cassette sub-family B member 10, mitochondrial; ABC transporter 10 protein; ATP binding cassette sub family B member 10; mitochondrial; ATP binding cassette transporter 10; EST20237; M ABC2; mitochondrial ATP binding cassette 2; MTABC2; ATP-binding cassette transporter 10; mitochondrial ATP-binding cassette 2; M-ABC2
• Gene ID: 23456
• mRNA Refseq: NM_012089
• Protein Refseq: NP_036221
• MIM: 605454
• UniProt ID: Q9NRK6
• Chromosome Location: 1q32
• Pathway: ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; Mitochondrial ABC transporters, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem
• Function: ATP binding; ATPase activity; ATPase activity, coupled to transmembrane movement of substances; nucleotide binding; oligopeptide-transporting ATPase activity; protein homodimerization activity; transporter activity