Recombinant Human ABCG1, GST-tagged

• Cat.No.: ABCG1-9228H
• Product Overview: Recombinant human ABCG1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-353a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 [ Homo sapiens ]
• Official Symbol: ABCG1
• Synonyms: ABCG1; ATP-binding cassette, sub-family G (WHITE), member 1; ATP-binding cassette sub-family G member 1; ABC8; ATP binding cassette transporter 8; ABC transporter 8; homolog of Drosophila white; ATP-binding cassette transporter 8; ATP-binding cassette transporter member 1 of subfamily G; white protein homolog (ATP-binding cassette transporter 8); WHITE1; MGC34313
• Gene ID: 9619
• mRNA Refseq: NM_004915
• Protein Refseq: NP_004906
• MIM: 603076
• UniProt ID: P45844
• Chromosome Location: 21q22.3
• Pathway: ABC transporters, organism-specific biosystem; ABC transporters, conserved biosystem; ABC-family proteins mediated transport, organism-specific biosystem; ABCA transporters in lipid homeostasis, organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem
• Function: ADP binding; ATP binding; ATPase activity; cholesterol binding; cholesterol transporter activity; glycoprotein transporter activity; nucleotide binding; phospholipid binding; phospholipid transporter activity; protein dimerization activity; protein hetero