Recombinant Human ABLIM2, His-tagged
Cat.No. : | ABLIM2-9252H |
Product Overview : | Recombinant Human ABLIM2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 282-389a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | ABLIM2 actin binding LIM protein family, member 2 [ Homo sapiens (human) ] |
Official Symbol : | ABLIM2 |
Synonyms : | ABLIM2; actin binding LIM protein family, member 2; abLIM-2; actin binding LIM protein 2; actin-binding LIM protein 2; actin-binding LIM protein family member 2; HGNC:19195; Ensembl:ENSG00000163995; MIM:612544; Vega:OTTHUMG00000057427 |
Gene ID : | 84448 |
MIM : | 612544 |
UniProt ID : | Q6H8Q1 |
Chromosome Location : | 4p16.1 |
Pathway : | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; DCC mediated attractive signaling, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Netrin-1 signaling, organism-specific biosystem |
Function : | actin binding; zinc ion binding |
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ABLIM2-109H | Recombinant Human ABLIM2 Protein, GST-Tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionYes. We provide comprehensive customized services to meet all customer needs.
Yes. We can customize the expression system and expression method according to customer needs.
ABLIM-2 strongly bind F-actin and modulate actin-dependent SRF activity via binding of STARS(striated muscle activator of Rho signaling).
In contrast to ABLIM-2, ABLIM-3 is predominantly expressed in human heart and brain, whereas the murine ABLIM-3 homologue displays a somewhat broader tissue distribution that also includes lung and liver.
ABLIM2 displays distinct tissue-specific expression patterns with the highest expression levels in muscle and neuronal tissue.
ABLIM2 is absent in Golgi and ER.
ABLIM2 may stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.
F-actin and ABRA can interact with ABLIM2.
yes, it is.
Predicted to enable actin filament binding activity. Predicted to be involved in lamellipodium assembly. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II.
Customer Reviews (3)
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Product quality is guaranteed. Will continue to cooperate in the future
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