Recombinant Human ADAM18, His-tagged

• Cat.No.: ADAM18-9371H
• Product Overview: Recombinant Human ADAM18 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 338-687a.a.
• Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a sperm surface protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ADAM18 ADAM metallopeptidase domain 18 [ Homo sapiens ]
• Official Symbol: ADAM18
• Synonyms: ADAM18; ADAM metallopeptidase domain 18; a disintegrin and metalloproteinase domain 18; disintegrin and metalloproteinase domain-containing protein 18; putative ADAM18 gene product; ADAM27; tMDCIII; disintegrin and metalloproteinase domain-containing protein 18; ADAM 18; tMDC III; transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III; MGC41836; MGC88272
• Gene ID: 8749
• mRNA Refseq: NM_001190956
• Protein Refseq: NP_001177885
• UniProt ID: Q9Y3Q7
• Chromosome Location: 8p11.22
• Function: metalloendopeptidase activity; metallopeptidase activity; zinc ion binding