Recombinant Human AFG3L2, His-tagged

• Cat.No.: AFG3L2-9459H
• Product Overview: Recombinant Human AFG3L2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 449-797a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: AFG3L2 AFG3 ATPase family gene 3-like 2 (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: AFG3L2
• Synonyms: AFG3L2; AFG3 ATPase family gene 3-like 2 (S. cerevisiae); AFG3 (ATPase family gene 3, yeast) like 2 , AFG3 ATPase family gene 3 like 2 (yeast) , SCA28, spinocerebellar ataxia 28; AFG3-like protein 2; paraplegin-like protein; ATPase family gene 3, yeast; SCA28; SPAX5; FLJ25993
• Gene ID: 10939
• mRNA Refseq: NM_006796
• Protein Refseq: NP_006787
• MIM: 604581
• UniProt ID: Q9Y4W6
• Chromosome Location: 18p11.21
• Function: ATP binding; metal ion binding; metalloendopeptidase activity; nucleoside-triphosphatase activity; nucleotide binding; peptidase activity; unfolded protein binding; zinc ion binding