Recombinant Human AFP, His-tagged
Cat.No. : | AFP-9461H |
Product Overview : | Recombinant Human AFP protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 260-609a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | AFP alpha-fetoprotein [ Homo sapiens ] |
Official Symbol : | AFP |
Synonyms : | AFP; alpha-fetoprotein; HPAFP; FETA; alpha-fetoglobulin; alpha-1-fetoprotein; |
Gene ID : | 174 |
mRNA Refseq : | NM_001134 |
Protein Refseq : | NP_001125 |
UniProt ID : | P02771 |
Chromosome Location : | 4q11-q13 |
Pathway : | Direct p53 effectors, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Glucocorticoid receptor regulatory network, organism-specific biosystem; |
Function : | metal ion binding; |
Products Types
◆ Recombinant Protein | ||
AFP-082H | Recombinant Human AFP Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
AFP-545H | Recombinant Human AFP Protein, MYC/DDK-tagged | +Inquiry |
AFP-1059H | Recombinant Human AFP Protein (Met1-Val609), HlgG1 Fc-tagged | +Inquiry |
AFP-0004H | Recombinant Human AFP Protein | +Inquiry |
AFP-289H | Recombinant Human AFP Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
AFP-8027H | Native Human Alpha FetoProtein | +Inquiry |
AFP-1180H | Native Human Alpha-Fetoprotein | +Inquiry |
AFP-3018P | Native pig AFP | +Inquiry |
◆ Lysates | ||
AFP-1706HCL | Recombinant Human AFP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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