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Recombinant Human ANKS1B, GST-tagged

Cat.No.: ANKS1B-9678H
Product Overview: Recombinant Human ANKS1B protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimers disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.
Source: E.coli
Species: Human
Tag: GST
Protein length: 446-510a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B [ Homo sapiens ]
Official Symbol: ANKS1B
Synonyms: ANKS1B; ankyrin repeat and sterile alpha motif domain containing 1B; ankyrin repeat and sterile alpha motif domain-containing protein 1B; AIDA 1; ANKS2; cajalin 2; EB 1; E2a-Pbx1-associated protein; amyloid-beta precursor protein intracellular domain associated protein 1; EB1; AIDA; EB-1; AIDA-1; cajalin-2; MGC26087;
Gene ID: 56899
mRNA Refseq: NM_001204065
Protein Refseq: NP_001190994
MIM: 607815
UniProt ID: Q7Z6G8
Chromosome Location: 12q23.1
Function: ephrin receptor binding;

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